中文内容为资料集译写。每条说明所依据的摘要或正文范围。 / Chinese text is prepared for this collection. Summary evidence is identified for each entry.
Nature全文 PDF斑点雀鳝基因组揭示脊椎动物演化并促进人类与真骨鱼类的比较
The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
Nature genetics · 2016
依据索引收录的作者摘要概括。
Summary based on the indexed author abstract.
主要发现 Key findings
缓慢演化的雀鳝基因组保留祖先染色体结构，并揭示在人与真骨鱼直接比较中难以识别的保守调控序列。
The slowly evolving gar genome retains ancestral chromosome structures and reveals conserved regulatory elements obscured in direct human–teleost comparisons.
结论 Conclusions
雀鳝提供全基因组复制前的参照，有助于理解真骨鱼基因分工及人类调控元件。
Gar provides a pre-duplication reference for interpreting teleost gene partitioning and human regulatory elements.
PNAS全文 PDF鱼类腕部与指部增强子的深度保守性
Deep conservation of wrist and digit enhancers in fish.
Proceedings of the National Academy of Sciences of the United States of America · 2015
摘要解读依据已查看的索引作者摘要；如已保存全文，可用于进一步阅读。
Summary based on the inspected indexed author abstract; archived full text, when available, is provided for further reading.
主要发现 Key findings
功能基因组实验在斑点雀鳝及斑马鱼中识别出 HoxA 和 HoxD 增强子。雀鳝序列能在小鼠腕部与手指区域驱动与小鼠增强子近似的表达，鱼类增强子也在胸鳍远端发挥作用。
Functional genomic assays identified HoxA and HoxD enhancers in spotted gar and zebrafish. Gar sequences drove reporter expression in mouse wrist and digit regions closely resembling mouse enhancer activity, while fish enhancers also acted in distal pectoral fins.
结论 Conclusions
结果支持附肢远端调控机制的深度保守性，并与硬骨鱼远端辐状骨和四足动物腕部或指部结构同源的假说一致。
The findings support deep conservation of distal-appendage regulatory machinery and are consistent with homology between bony fish distal radials and tetrapod wrist or digit structures.